Redefining Cancer Diagnostics withMetabolite Profiling
Nearly everyone has been touched by cancer. A parent. A spouse or child. A friend or colleague. Cancer is pervasive. It is deadly. And the threat is very real.
Cancer is also challenging for oncologists to diagnose and treat and difficult for patients to endure. Current diagnostic tests are often unreliable, leading to more tests, more costs and patient anxiety. Many cancers are detected late when treatment options are few. New molecular diagnostics using DNA, RNA, and proteomics have not delivered actionable tests as expected.
In many respects, Matrix-Bio, an Indiana-based company focused on developing cancer diagnostic tests using metabolite profiling, was born of the frustration of oncologists and their patients. Led by founder and chief scientific officer Daniel Raftery, PhD, MBA, Matrix-Bio developed the VeraMarker™ metabolite profiling technology platform that enables highly accurate blood serum based diagnostic tests for early cancer diagnosis, recurrence monitoring, and tracking the effects of treatment while in progress.
Our mission is to improve patient outcomes by redefining how cancer is diagnosed.
Our approach is this. We have combined advanced methods in nuclear magnetic resonance (NMR) and mass spectrometry (MS), the “gold standards” for analyzing biomarkers in blood and urine. The resulting technology, the VeraMarker™ metabolite profiling platform, enables the identification of biomarkers that indicate early cancer and its recurrence after therapy. The sensitivity and specificity of Matrix-Bio’s metabolite profiling tests, which rely on a simple blood draw rather than tissue samples, is significantly greater than current detection and monitoring tests. By accurately and reliably detecting cancer at earlier, more treatable stages, patients and oncologists have more treatment options, the chance of a better prognosis, and the peace of mind knowledge provides.
Matrix-Bio has momentum. The biomarkers behind our VeraMarker™ BCR (Breast Cancer Recurrence) Test have been licensed by Quest Diagnostics, which is developing a commercial test for launch in early 2015. Building on this success, we’re now developing the VeraMarker™ CCM (Colon Cancer Monitoring) test. We seek to raise $750,000 to validate our CCM test, the first of three tests for the more than $2 billion colon cancer testing market.